The Reach with its fertile lands left the Iron Throne peacefully in 317 AL. This does not mean it did not suffer its own problems. King Mace fought for four years to drive out the Ironborn, and died in the process. King Willas The Cripple drove the Florents into exile to seize their lands for Garlan around 322 AL. Garlan was assassinated by one of the Sand Snakes a year later. Willas finally succumbed to his disablilty in 330 AL leaving The Reach to Queen Margaery and her husband Tommen. She ruled for the rest of her days, and her children inherited The Reach as Tyrells. The next few centuries were relatively peaceful, save for a few wars with Dorne and The United Kingdom. During the great rebirth, The Reach became the center of scholarly learning as new discoveries were being made. The Citadel of Oldtown evolved into Westeros' first University after Maester's broke their chains in 445 AL. Science was about discovering the new in life, not prattling about the same thing over and over. The best students from across Westeros come here for education. The Reach is still very much the breadbasket of Westeros, but is also its best naval power and leaders in genetic technologies.